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Fig. 4 | Cancer Cell International

Fig. 4

From: Single-cell RNA sequencing reveals cellular and molecular heterogeneity in extensive-stage small cell lung cancer with different chemotherapy responses

Fig. 4

Characterization of T/NK cells between PD group and PR group. A UMAP projection of subclustered T/NK cells from 9 treatment-naive ES-SCLC samples. Each dot corresponds to a single cell, colored by cell type and group. B Heatmap of marker gene expression in T/NK cell subtypes. C The proportion of T/NK cell subtypes among three groups. D Differentially expressed pathways are scored per cell by GSVA among T/NK cell subtypes. E Potential developmental trajectory of CD4+ T cells inferred by Monocle. Each dot corresponds to a single cell, colored by pseudotime value, cell type and group

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Cancer Cell International

ISSN: 1475-2867

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